Endocrine Abstracts

IntroductionThe use of a specific questionnaire to assess quality of life(QoL) in adults with growth hormone deficiency (GHD) and its improvement after treatment requires further studies, in particular, their relationship to basal scores and Insulin like growth factor (IGF-1) values. We analysed our data to determine if the QoL as assessed by the QoL-AGHDA improved in adult GHD patients following growth hormone (GH) replacement.MethodsPatients referred with symptom...

InroductionDue to persistent qualitative abnormalities in GH secretion following treatment, it is extremely difficult to diagnose GHD in treated acromegalic patients. We aimed to study the response of successfully treated acromegalic patients to the combined growth hormone releasing hormone and arginine test and compare it with the insulin tolerance test.Patients and MethodsTwelve acromegalic patients, in whom mean serum GH level off medical treatment was below 5mU...

Introduction: Factors that affect the response to growth hormone (GH) treatment in GH-deficient adults are not certain. We performed a retrospective analysis of our data to determine the effect of age and sex hormone replacement on growth hormone replacement dose and IGF-1 levels in growth hormone deficient adults.Patients and Methods: 146 patients (73F/73M, age range 18-84 years) were referred for growth hormone replacement between 1997 and 2001. The I...